Head-to-head comparison updated for 2026. See which protein product comes out on top.
| Attribute | ||
|---|---|---|
| Brand | Dymatize | Optimum Nutrition |
| Protein / serving | 25gBest | 24g |
| Calories / serving | 110Best | 120 |
| Fat / serving | 0.5gBest | 1.5g |
| Carbs / serving | 2gBest | 3g |
| Sugar / serving | 1gBest | 1g |
| Price / serving | $1.03 | $0.86Best |
| Price / gram protein | $0.0411 | $0.0360Best |
| Overall score | 79/100Best | 76/100 |
| Value score | 65/100 | 78/100Best |
| Purity score | 93/100Best | 73/100 |
| Protein source | Whey Isolate | Whey Blend |
| Sweetener | sucralose | sucralose |
| Certifications | Informed Sport | Informed Sport |
| Dietary tags | Gluten-Free | Gluten-Free |
| Third-party tested | Yes | Yes |
| Buy on Amazon | Buy on Amazon |
Dymatize ISO100 is one of the highest-quality whey protein isolates on the market. What sets it apart is the hydrolysis process, which pre-breaks down the protein into smaller peptides for faster absorption. Each serving delivers 25g of protein with only 110 calories, 0.5g of fat, and 2g of carbs, making it one of the leanest protein options available.
Optimum Nutrition Gold Standard 100% Whey is the best-selling whey protein powder in the world, and for good reason. With 24g of protein per scoop from a tri-blend of whey isolate, concentrate, and peptides, it delivers a well-rounded amino acid profile including 5.5g of BCAAs and 11g of EAAs per serving. The Double Rich Chocolate flavor is consistently praised as one of the best-tasting protein powders on the market.
Dymatize ISO100 Hydrolyzed edges ahead with an overall score of 79 vs 76. For value, Optimum Nutrition Gold Standard 100% Whey wins with a 78/100 value score.
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Last updated: March 2026
